Culpeper's astute eye, keen wit, and encyclopedic knowledge led him to create his definitive English Physitian, more commonly known today as Culpeper's Complete Herbal. Planetary influences were key to his understanding of herbal medicine. In his philosophy, each plant is governed by a planet, and the time a person takes to their sickbed is significant to their diagnosis and healing. His Semeiotica uranica, or, An astrological judgement of diseases from the decumbiture of the sick was a seminal early work of medical astrology and is published here as a historical document of great fascination to astrologers and historians of herbalism and medicine. This edition includes modernized English spelling and expert guidance on how to decipher the work and consider Culpeper's influence in modern context. This edition includes a foreword by Alice Sparkly Kat, author of Postcolonial Astrology, and an introduction by Judith Hill, author of Medical Astrology.